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MRNA (guanine-N7-)-methyltransferase : ウィキペディア英語版
MRNA (guanine-N7-)-methyltransferase

In enzymology, a mRNA (guanine-N7-)-methyltransferase also known as mRNA cap guanine-N7 methyltransferase is an enzyme that catalyzes the chemical reaction
:S-adenosyl-L-methionine + G(5')pppR-RNA \rightleftharpoons S-adenosyl-L-homocysteine + m7G(5')pppR-RNA (mRNA containing an N7-methylguanine cap)
Thus, the two substrates of this enzyme are S-adenosyl methionine and G(5')pppR-RNA, whereas its two products are S-adenosylhomocysteine and m7G(5')pppR-RNA. This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases.
In humans, mRNA cap guanine-N7 methyltransferase is encoded by the ''RNMT'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8731 )
== Nomenclature ==

The systematic name of this enzyme class is S-adenosyl-L-methionine:mRNA (guanine-N7-)-methyltransferase. Other names in common use include:
* messenger ribonucleate guanine 7-methyltransferase,
* guanine-7-methyltransferase,
* messenger RNA guanine 7-methyltransferase, and
* S-adenosyl-L-methionine:mRNA (guanine-7-N-)-methyltransferase.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「MRNA (guanine-N7-)-methyltransferase」の詳細全文を読む



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